The PLAG1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PLAG1, and PLAG1 zinc finger. This antibody recognizes Human antigen. The PLAG1 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene